The epidemiology and examination of clinical outcomes in children with COVID-19: A research overview

Review Article

Author Details : Bindu John*

Volume : 7, Issue : 3, Year : 2021

Article Page : 119-122

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Introduction: COVID- 19 pandemic has affected hundreds of thousands of people worldwide, and so far, accounted for 0.39-12.3% of affected disease population. Even though a large number of studies have reviewed symptoms and characteristics of adults with COVID-19, only some of them have included a smaller number of children.
Objectives: This study aimed a) To examine the epidemiological characteristics of SARS-CoV-2 infection reported in children from published studies b) To outline the signs and symptoms of SARS-CoV-2 infection reported in children from the research studies and c) To provide converging evidence of the clinical outcomes and prognosis of children affected with SARS-CoV-2 infection from reported studies.
Materials and Methods: A literature review was conducted through online sources of data base available in the internet. Studies published from Jan 2020 up to September 2021 were included.
Results: The organism causing infection was the novel Corona virus (SARS-CoV-2). In children, almost 0.39-12.3% of the population was affected. A slight predominance of boys vs. girls was noted, but it was not statistically significant. The incubation period ranged from 2-14 days. Nearly 51% of children were presenting with mild disease and nearly 4% were asymptomatic. The children also presented with non-respiratory symptoms, but the exact figures were not available. Multisystem inflammatory response was the most common reported complication.
Conclusion: Current findings indicate that children have a lower incidence of the disease, with milder predominance and better prognosis, but prolonged shedding of virus in the nasal and stools sample and being asymptomatic raises a concern of community transmission.

Keywords: Children, SARS­CoV­2, Epidemiology, Clinical outcomes, Signs and Symptoms, Clinical presentation, Etiology

How to cite : John B, The epidemiology and examination of clinical outcomes in children with COVID-19: A research overview. IP Int J Med Paediatr Oncol 2021;7(3):119-122

Copyright © 2021 by author(s) and IP Int J Med Paediatr Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

Article History

Received : 10-09-2021

Accepted : 18-09-2021

Available online : 14-10-2021

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